It is predominately iatrogenic treatmentinduced, and is characterized by acute paralysis, dysphagia difficulty swallowing, dysarthria difficulty speaking, and other neurological symptoms. The damage is from two stenosis, four discal hernie and also mielomalatia. Hta, sin repercusiones, trata con hct y amlodipina. Mielinolisis central pontina en trasplante hepatico. Pediatricians and surgeons should combine the knowledge of their own field for successful treatment.
Please use one of the following formats to cite this article in your essay, paper or report. The original patient population included only chronic alcoholics. Magnetic resonance mr features of a patient with profound hyponatremia and clinical findings of central pontine myelinolysis are presented. Central pontine myelinolysis cpm is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons an area of the brainstem. Riskadapted treatment strategies were established because of the high median age 6075 years of. Atlas of neuroanatomy and neurophysiologyselections from the netter collection of medical illustrations illustrations by frank h. Mielinolisis extrapontina secundaria a hiponatremia por. Extrapontine myelinolysis is an acute unusual process, included in demyelinating syndromes of metabolic etiology, which differentiate from central pontine myelinolysis, by affecting other brain areas with clinical manifestation such as dystonia, catatonia, postural tremor, myoclonic spasm, parkinsonism or pyramidal sings. There is a controversy wheter central pontine myelinolysis can complicate either hyponatremia or its rapid correction.
Pdf central pontine myelinolysis is a demyelinating lesion in the basis pontis which in most cases is caused by a rapid correction of hyponatremia. Mielopatia cervical western new york urology associates, llc. It is a condition most frequently related to rapid correction of hyponatremia. Central pontine myelinolysis radiology reference article. Surgery is usually required for treatment of cervical myelopathy to decompress the neural elements, restore lordosis, and stabilize the spine. Clinical evolution of central pontine myelinolysis in a. Central pontine myelinolysis cpm was first termed in 1959 by adams to describe a symmetric, demyelinating focus prominent in the central pons. Labardini mendez, eduardo cervera ceballos, carmen corrales alfaro, micaela balbuena martinez, arlette araceli barbosa ibarra, jose ramiro espinoza zamora, omar genaro lopez navarro, cristal medina perez.
Central pontine myelinolysis cpm is now more commonly referred to as osmotic demyelination syndrome, which recognizes that the same phenomenon is also seen in other areas of the brain previously known as extrapontine myelinolysis. Central pontine myelinolysis cpm, a potentially fatal and debilitating neurological condition, was first described in 1959 in a study on alcoholic and malnourished patients. Mds is a clonal disorder characterized by ineffective hematopoiesis, which can lead to either fatal cytopenias or acute myelogenous leukemia aml. Mielinolisis pontina central e hiponatremia perioperatoria. Leucemia mieloide cronica e neoplasie mieloproliferative croniche ph negative i tumori ematologici. Avms and it is usually combine with the surgery or the radiosurgery.
Thanks to the ninjadoc, i have been made aware of another way that a person can develop hyponatremia, which increases their risk for cpm. Coreman, i have done a scanner and it seems i have damaged neck bones from c1 to c6. The pediatrician is able to give an essential contribution to. This condition, however, has also been found in the malnourished, transplant recipients, or chronically debilitated patients,in particular, those in whom electrolyte. Resolution of the mr findings paralleled the clinical recovery. Myelinolysis, demyelination, hyponatremia, pregnancy. As such the condition is described in the osmotic demyelination syndrome article. Central pontine myelinolysis with clinical recovery. Diabetic ketoacidosis, alcoholic ketoacidosis, starvation ketosis and hypoglycaemic ketoacidosis. Pdf perioperative fluid therapy in the pediatric patient. Chronic alcoholism associated cpm tends to be benign with a favorable prognosis compared to cpm secondary to rapid correction of hyponatremia. Hyponatremia after very heavy beer drinking researchgate. Mielinolisis extrapontina en paciente con hipernatremia. Pdf mielinolisis central pontina en trasplante hepatico.
Feb 27, 2019 please use one of the following formats to cite this article in your essay, paper or report. Download as ppt, pdf, txt or read online from scribd. Central pontine myelinolysis following rapid correction of hyponatremia. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.
1300 1284 290 1207 1152 1485 438 788 962 296 1005 322 1457 214 756 1200 249 1571 1378 392 586 1074 553 1588 38 1392 267 1438 987 370 14 1335 945 1033 63